A Critical Review on the Applications of Metal Materials for Medical Implants

  IJETT-book-cover  International Journal of Recent Engineering Science (IJRES)          
© 2019 by IJRES Journal
Volume-6 Issue-4
Year of Publication : 2019
Authors : A.G Usman, Osama A.M


MLA Style: A.G Usman, Osama A.M "A Critical Review on the Applications of Metal Materials for Medical Implants" International Journal of Recent Engineering Science 6.4(2019):7-12. 

APA Style: A.G Usman, Osama A.M, A Critical Review on the Applications of Metal Materials for Medical Implants. International Journal of Recent Engineering Science, 6(4),7-12.

This review was focusing on different types of metallic materials that are used as an implant due to their chemical, thermal, electrical, and mechanical properties. Therefore, to design and manufacture new as well a cost-effective metal-alloy having higher biocompatibility that can be used as implant specific properties should be considered before their manufacturing. Also, using common alloys for creating a strategy to minimize the use of some rare metals is considered as one of the challenges in using metals as an implant. In order to ensure long human life, especially when using implants on young patients, the need for developing a novel method and strategy of using a metallic alloy in the bio-medical field is aimed at giving structural metallic materials having suitable mechanical, chemical and biomedical biocompatibility. Therefore, metallic alloys that can be used in the future and for the next generation should have less toxic effects. Elements that can cause severe and adverse health menace, such as tumor-causing agents, neurological disorder, and coronary disorder agents, should be avoided. Therefore, these metals and their alloys should have low cost having lower melting points such as Mg, Fe, Ti, Mn, and their alloys. Finally, the need for designing chemically, biologically, mechanically, and electrically biocompatible metal alloys are significantly recommended, especially those having longer-term implantation.

[1] J. R. Davis, HANDBOOK OF MATERIALS FOR MEDICAL DEVICES. United States of America: ASM International, Materials Park, 2003.
[2] D. Vojtěch, J. Kubásek, J. Šerák, and P. Novák, “Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation,” Acta Biomater., vol. 7, no. 9, pp. 3515–3522, 2011.
[3] M. Schinhammer, A. C. Hänzi, J. F. Löffler, and P. J. Uggowitzer, “Design strategy for biodegradable Fe-based alloys for medical applications,” Acta Biomater., vol. 6, no. 5, pp. 1705–1713, 2010.
[4] B. Zberg, P. J. Uggowitzer, and J. F. Löffler, “MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants.,” Nat. Mater., vol. 8, no. 11, pp. 887–91, 2009.
[5] L. Zhang, F. X. Gu, J. M. Chan, A. Z. Wang, R. S. Langer, and O. C. Farokhzad, “<Campa_2008_Association of ABCB1 and OPRM1 with Morphine.pdf>,” no. June, 2008.
[6] P. K. Bowen, J. Drelich, and J. Goldman, “Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents,” Adv. Mater., vol. 25, no. 18, pp. 2577–2582, 2013.
[7] N. Hort et al., “Magnesium alloys as implant materialsPrinciples of property design for Mg-RE alloys,” Acta Biomater., vol. 6, no. 5, pp. 1714–1725, 2010.
[8] H. Hermawan, A. Purnama, D. Dube, J. Couet, and D. Mantovani, “Fe-Mn alloys for metallic biodegradable stents: Degradation and cell viability studies,” Acta Biomater., vol. 6, no. 5, pp. 1852–1860, 2010.
[9] J. R. Davis, Properties and Selection: Nonferrous Alloys and Special-Purpose Materials. ASM International, Materials Park, 1990.
[10] X. Gu, Y. Zheng, Y. Cheng, S. Zhong, and T. Xi, “In vitro corrosion and biocompatibility of binary magnesium alloys,” Biomaterials, vol. 30, no. 4, pp. 484–498, 2009.
[11] M. Moravej, F. Prima, M. Fiset, and D. Mantovani, “Electroformed iron as new biomaterial for degradable stents: Development process and structure-properties relationship,” Acta Biomater., vol. 6, no. 5, pp. 1726–1735, 2010.
[12] D. Vojtech, J. Kubasek, J. ?apek, and I. Pospisilova, “Magnesium, zinc and iron alloys for medical applications in biodegradable implants,” in International Conference on Metallurgy and Materials, Conference Proceedings, 2014, pp. 1–6.
[13] J. Kubásek, D. Vojtěch, J. Lipov, and T. Ruml, “Structure, mechanical properties, corrosion behavior and cytotoxicity of biodegradable Mg-X (X = Sn, Ga, In) alloys,” Mater. Sci. Eng. C, vol. 33, no. 4, pp. 2421–2432, 2013.
[14] Kurtz, S., Ong, K., Lau, E., Mowat, F., Halpern, M., 2007. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. The Journal of Bone and Joint Surgery 89, 780–785.
[15] Md. Masud Rana, Naznin Akhtar, Md. Zahid hasan and S.M. Asaduzzaman, "Preparation And Evaluation Of Biocompatible Composite For Bone Tissue Engineering" SSRG International Journal Of Pharmacy And Biomedical Engineering 4.3 (2017): 7-14.
[16] He, G., Hagiwara, M., 2006. Ti alloy design strategy for biomedical applications. Materials Science and Engineering C 26, 14–19
[17] Niinomi, M., Nakai, M., 2011. Titanium-based biomaterials for preventing stress shielding between implant devices and bone. International Journal of Biomaterials 2011, 836587 -10
[18] J.C.M., 2000. Microsctructure and properties of materials. World Scientific 2, 49–55.
[19] Mansour, H.A., Ray, J.D., Mukherjee, D.P., 1995. Proceeding of the Biomedical Engineering Conference, 7–9 Apr, 53.
[20] Song, Y., Xu, D.S., Yang, R., Li, D., Wu, W.T., Guo, Z.X., 1999a. Theoretical study of the effects of alloying elements on the strength and modulus of beta-type bio-titanium alloys. Materials Science and Engineering A 260 (1–2), 269–274
[21] Oshida, Y., 2006. Bioscience and Bioengineering of Titanium Materials. Elsevier Science, Oxford.

Implant, metal, alloy, biocompatibility, chemical, mechanical and biodegradable.